Hydrocodone (Vicodin)
Hydrocodone (vicodin) - an effective narcotic anaesthetising and antibechic medicine. Presence in paracetamol drug enhances analgetic effect, but confines the maximum daily dose taking into account probability of accumulation of paracetamol in toxic concentrations. The vicodin is awake sedative and a medicine for tussis which strikes root inside. The Therapeutic dose at a rate of 5-10 milligrammes is equivalent to 60 milligrammes of Morphinum which is used inside.
On danger of habituation it is comparable with codeine. Long method of Hydrocodonum in the big doses can invoke weak euphoria, and further – a pathological addiction. At an overdosage there is a headache, dryness in a mouth, the general delicacy, starts to pull in a sleep. The same symptoms that educe at a venenating with codeine.
The hydrocodone is awake sedative and a medicine for tussis which strikes root inside. It is in the list of II narcotics but which are on sale among narcotics from the list III. The Therapeutic dose at a rate of 5-10 milligrammes is equivalent to 60 milligrammes of Morphinum which is used inside. Sale and effecting of this narcotic have considerably increased during the last years, also as well as their illegal use.
Clinico-pharmacological profile of Hydrocodonum same, as at codeine. It is well absorbed at enteral method (about 50 %) and the expressed antibechic an effect has. A hydrocodone use only enterally routinely in a combination with other not narcotic analgetics for reception of anaesthetising effect.
Utilisation in clinic
Hydrocodone (vicodin) routinely let out in a combination with Acidum acetylsalicylicum. The similar combination provides an action synergy, anaesthetization level corresponds to action of the doubled dose of each of these drugs. Auxiliary effects thus weaken.
Vicodin side effects include allergic responses, attacks, the sticky skin, the raised delicacy, giddiness, a hyperventilation, a loss of consciousness, a yellowing of eyes or a skin, unusual weariness, bleedings, hematomas, dryness in a mouth, a nausea, vomiting, a hyporexia, muscular cramps, a diaphoresis, inflows, an itch, a ring in ears, a hearing loss, the reduced emiction and depression of a sexual appetence.